Flu Virus -Advancements in Detection & Differentiation

Influenza outbreaks and epidemics pose ongoing risks to global human public health. Recently, human infections with A/H5N1 avian influenza viruses have heightened the potential for the emergence of an influenza A virus with pandemic potential. Laboratory identification of human influenza virus infections is commonly performed using direct antigen detection, virus isolation in cell culture, or detection of influenza-specific RNA by reverse transcriptase-polymerase chain reaction (RT-PCR). In recent years commercial influenza rapid diagnostic tests have become available. These are mostly antigen detection tests, which can produce results within 30 minutes. They can provide results in a clinically relevant time frame to complement the use of antiviral medications for treatment and chemoprophylaxis of influenza. Their wide availability has resulted in their increasing application to clinical situations, which may be inappropriate or where scientific data are lacking.

  • Assays and symptoms
  • Rapid detection methods by PCR
  • Nanotechnology and strain differentiation
  • Clinical impact & diagnostics approaches
  • Strain identification assays and rapid diagnostic testing for viral infections
  • Biomarkers for influenza

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